Blastocyst Culture and Transfer

What Is Blastocyst Culture And Transfer

Blastocyst culture and transfer is a cutting-edge reproductive technology used in assisted reproductive treatments like IVF. This advanced technique involves cultivating embryos in a laboratory setting for 2-5 days, allowing them to develop into blastocyst-stage embryos.

A blastocyst is the final stage of embryo development before implantation in the uterine wall. By growing embryos to this stage, our fertility specialists can select the healthiest and most viable embryos for transfer, increasing the chances of a successful pregnancy.

In this process, the frozen blastocyst transfer is typically performed on the fifth day, offering the best possible outcome for individuals undergoing fertility treatment.

Blastocyst
Culture and Transfer

Blastocyst culture and transfer is an advanced reproductive technology used in IVF treatments. This process involves growing embryos in a laboratory for 5-6 days, allowing them to develop into blastocysts.

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Benefits of Blastocyst Culture

Increased success rates compared to Day 3 embryo transfer
Improved selection of viable embryos for transfer
Reduced risk of multiple pregnancies
Enhanced implantation potential

When is Blastocyst Culture Recommended?

Couples with previous IVF or ICSI failures
Those opting for Elective Single Embryo Transfer (eSET)
Couples undergoing Preimplantation Genetic Diagnosis (PGD)
When multiple healthy embryos are available on Day 3

The Blastocyst Transfer Process

Egg collection and fertilization
Embryo culture and growth to the blastocyst stage
Selection and transfer of the healthiest blastocyst
Pregnancy test and follow-up ultrasound

While blastocyst culture offers many benefits, there are risks involved, including embryonic block and reduced embryo availability for freezing and transfer.

Why Blastocyst culture and transfer is Done?

At our fertility centre, we offer blastocyst culture and transfer as a specialized treatment option for individuals struggling with infertility. Our expert team utilizes advanced reproductive technology to cultivate embryos in a laboratory setting, allowing them to develop into blastocysts.

Blastocyst culture and transfer is performed to marginally increase the chances of implantation leading to a successful pregnancy; they have a higher potential to lead to a pregnancy in comparison to three-day-old embryos. As it is the healthiest embryo, it enables a single embryo transfer (SET). Thus, this negates the need for transferring multiple embryos that can lead to a multiple pregnancy, that is, more than one pregnancy, causing obstetric complications. Additionally, the remaining healthy embryos can be cryopreserved and used in subsequent ART procedures performed in the future; this is called frozen embryo transfer (FET).

In a natural pregnancy, a blastocyst implants itself in the uterus and gives a positive pregnancy test 10 days to two weeks after fertilisation. Thus, blastocyst transfer mimics this natural process, increasing the chances for implantation. On the contrary, a three-day old embryo is present in the fallopian tube hence, it is free-flowingly present in the uterus before its implantation making its implantation success less likely.

A beta-human chorionic gonadotropin (>β>hCG) test is performed seven days after blastocyst transfer to ascertain if implantation has taken place. A blastocyst transfer is especially advantageous in females who are young and have some ovarian reserve. This procedure can be performed after IVF or ICSI.

In addition to the aforementioned advantages of blastocyst transfer, it is a preferred option in cases of female infertility with the following diagnosis:

Problem with ovulation: Ovulation disorders can indicate a low ovarian reserve, the existence of health conditions such as polycystic ovarian syndrome (PCOS) and endometriosis or perimenopause.
Problem with fallopian tube: Damages to the fallopian tube, including infections, blockages or surgery to tie or remove them, compromise with the passage through which a) an egg travels from the ovary into the uterus, and b) an embryo moves down the uterus. This acts as a barrier to conception.
Uterine fibroids: Benign tumors of the uterus are known as fibroids. They can come in the way of a fertilised embryo to get implanted in the uterus.

Our team of fertility specialists has extensive experience in performing blastocyst culture and transfer procedures. We take a personalized approach to each patient's care, ensuring the best possible outcomes.

If you're considering blastocyst culture and transfer, contact our centre to schedule a consultation and take the first step towards achieving your reproductive goals.

Blastocyst Culture and Transfer Procedure

At AROGYAM IVF, we offer advanced blastocyst culture and transfer services as part of our assisted reproductive technology (ART) cycle. Our expert team guides you through every step of the process, ensuring personalized care and optimal outcomes.

A microscope positioned on a surface, featuring a glass slide placed on its stage for examination.

Our Blastocyst Culture and Transfer Process

Stage 1: Birth Control Pills or Oestrogen

Your doctor may recommend oestrogen or birth control tablets before you begin IVF therapy. This is used to regulate the time of your menstrual cycle and prevent the growth of ovarian cysts. It enables your doctor to manage your treatment and increase the number of mature eggs collected during the egg retrieval operation.
Stage 2: Ovarian Stimulation

In a normal woman, each menstrual cycle results in the production of one egg. However, several eggs are necessary for IVF. The likelihood of creating a healthy embryo improves when more than one egg is used. To boost your body's egg production, you'll be given fertility medications. You'll be prescribed injectable hormone medications during your IVF cycle to encourage all of the eggs in that cycle to develop at once and completely.
Stage 3: Ultrasound Examination

To evaluate how well the medications on your ovaries are working, a vaginal ultrasound test is performed at regular intervals. If the outcome is bad, it's possible that your doctor will suggest stopping the IVF treatment cycle. You and your doctor will decide together on this.
Stage 4: Egg Retrieval

The egg retrieval procedure is carried out 36 hours following your hormone IVF injections given for stimulation. Transvaginal sonography is used to help retrieve eggs from the ovaries while the patient is under general anesthesia. Your reaction to the medications will determine how many eggs are collected, and the operation lasts 15 to 30 minutes. Around two to three hours following the treatment, you can leave for home. Sometimes there may be some stomach pain and vaginal spotting, but these symptoms usually go away in a day or two.
Stage 5: Sperm Collection

A sample of semen is required from your spouse. On the day the eggs are harvested, a sample of fresh semen is often taken. A previously frozen sample can also be used, though, if a fresh sample can't be made on the same day or if the spouse isn't there on the day, the eggs are collected. The sperm and the eggs will be combined by a technician in a petri dish. If it fails to result in embryos, your doctor can choose to perform ICSI.
Stage 6: Fertilizing the Eggs

The eggs will be fertilized in the laboratory, either through ICSI or traditional IVF. The embryologist will check the eggs the following day to see whether they have been fertilized and then later to see if any embryos have developed further. It is possible to freeze additional well-developed embryos if there are more than three for eventual later transfer.
Stage 7: Embryo Culture

The fertilized eggs (embryos) are nurtured in a controlled environment, allowing them to grow and develop.
Stage 8: Embryo Transfer

This is done two, three, or five days following egg harvest. To decide if a day 3 or day 5 transfer is necessary, embryologists keep an eye on the development and viability of the embryos. The embryo is positioned in your uterus using a tiny catheter that is implanted. It takes between six and ten days for the implantation to take place if the operation is successful. A course of medicines to assist the luteal phase will be provided to you after the transfer.
Stage 9: Pregnancy Test

A pregnancy blood test is carried out after two weeks following extraction. In the event that the test is positive, the patient is thought to be four weeks pregnant.

Our team at AROGYAM IVF is committed to providing compassionate and personalized care throughout your journey. Contact us to schedule a consultation and take the first step towards achieving your reproductive goals.

Why Choose Arogyam IVF?

At Arogyam IVF, we offer a comprehensive range of fertility treatments, backed by a strong network, experienced doctors,

and a patient-centric approach. Here's what sets Arogyam IVF apart:

Exceptional Success Rates: Arogyam IVF has achieved remarkable success rates, thanks to our cutting-edge technology, expert doctors, and personalized care.
State-of-the-Art Infrastructure: Our modern fertility clinic is equipped with the latest technology, ensuring efficient and effective treatment.
Experienced Fertility Specialists: Our team of experienced fertility doctors works closely with each patient, providing expert guidance and tailored treatment plans.
Personalized Fertility Treatment: We recognize that each couple's fertility journey is unique. Our personalized approach focuses on individual medical history, diagnosis, and specific needs.
Comprehensive Fertility Services: Arogyam IVF offers a wide range of fertility treatments, including IVF, ICSI, IUI, Cryopreservation, and Donor Programs.
Patient-Centric Care: Our dedicated team provides compassionate support and guidance throughout your fertility journey, ensuring a seamless and stress-free experience.

Do’s and Don’ts

Stage 1: Birth Control Pills or Oestrogen

Your doctor may recommend oestrogen or birth control tablets before you begin IVF therapy. This is used to regulate the time of your menstrual cycle and prevent the growth of ovarian cysts. It enables your doctor to manage your treatment and increase the number of mature eggs collected during the egg retrieval operation.
Stage 2: Ovarian Stimulation

In a normal woman, each menstrual cycle results in the production of one egg. However, several eggs are necessary for IVF. The likelihood of creating a healthy embryo improves when more than one egg is used. To boost your body's egg production, you'll be given fertility medications. You'll be prescribed injectable hormone medications during your IVF cycle to encourage all of the eggs in that cycle to develop at once and completely.
Stage 3: Ultrasound Examination

To evaluate how well the medications on your ovaries are working, a vaginal ultrasound test is performed at regular intervals. If the outcome is bad, it's possible that your doctor will suggest stopping the IVF treatment cycle. You and your doctor will decide together on this.
Stage 4: Egg Retrieval

The egg retrieval procedure is carried out 36 hours following your hormone IVF injections given for stimulation. Transvaginal sonography is used to help retrieve eggs from the ovaries while the patient is under general anesthesia. Your reaction to the medications will determine how many eggs are collected, and the operation lasts 15 to 30 minutes. Around two to three hours following the treatment, you can leave for home. Sometimes there may be some stomach pain and vaginal spotting, but these symptoms usually go away in a day or two.
Stage 5: Sperm Collection

A sample of semen is required from your spouse. On the day the eggs are harvested, a sample of fresh semen is often taken. A previously frozen sample can also be used, though, if a fresh sample can't be made on the same day or if the spouse isn't there on the day, the eggs are collected. The sperm and the eggs will be combined by a technician in a petri dish. If it fails to result in embryos, your doctor can choose to perform ICSI.
Stage 6: Fertilizing the Eggs

The eggs will be fertilized in the laboratory, either through ICSI or traditional IVF. The embryologist will check the eggs the following day to see whether they have been fertilized and then later to see if any embryos have developed further. It is possible to freeze additional well-developed embryos if there are more than three for eventual later transfer.
Stage 7: Embryo Culture

The fertilized eggs (embryos) are nurtured in a controlled environment, allowing them to grow and develop.
Stage 8: Embryo Transfer

This is done two, three, or five days following egg harvest. To decide if a day 3 or day 5 transfer is necessary, embryologists keep an eye on the development and viability of the embryos. The embryo is positioned in your uterus using a tiny catheter that is implanted. It takes between six and ten days for the implantation to take place if the operation is successful. A course of medicines to assist the luteal phase will be provided to you after the transfer.
Stage 9: Pregnancy Test

A pregnancy blood test is carried out after two weeks following extraction. In the event that the test is positive, the patient is thought to be four weeks pregnant.

At AROGYAM IVF, we want to ensure that you have the best possible outcome after your blastocyst transfer. Here are some important dos and don'ts to follow

By following these dos and don'ts, you can help ensure a successful outcome and a healthy pregnancy. If you have any questions or concerns, don't hesitate to contact our team at AROGYAM IVF.

Pregnant woman in a flowing white dress gently cradles a baby socks, symbolizing love and motherhood.

Frequently Asked Question's

Stage 1: Birth Control Pills or Oestrogen

Your doctor may recommend oestrogen or birth control tablets before you begin IVF therapy. This is used to regulate the time of your menstrual cycle and prevent the growth of ovarian cysts. It enables your doctor to manage your treatment and increase the number of mature eggs collected during the egg retrieval operation.
Stage 2: Ovarian Stimulation

In a normal woman, each menstrual cycle results in the production of one egg. However, several eggs are necessary for IVF. The likelihood of creating a healthy embryo improves when more than one egg is used. To boost your body's egg production, you'll be given fertility medications. You'll be prescribed injectable hormone medications during your IVF cycle to encourage all of the eggs in that cycle to develop at once and completely.
Stage 3: Ultrasound Examination

To evaluate how well the medications on your ovaries are working, a vaginal ultrasound test is performed at regular intervals. If the outcome is bad, it's possible that your doctor will suggest stopping the IVF treatment cycle. You and your doctor will decide together on this.
Stage 4: Egg Retrieval

The egg retrieval procedure is carried out 36 hours following your hormone IVF injections given for stimulation. Transvaginal sonography is used to help retrieve eggs from the ovaries while the patient is under general anesthesia. Your reaction to the medications will determine how many eggs are collected, and the operation lasts 15 to 30 minutes. Around two to three hours following the treatment, you can leave for home. Sometimes there may be some stomach pain and vaginal spotting, but these symptoms usually go away in a day or two.
Stage 5: Sperm Collection

A sample of semen is required from your spouse. On the day the eggs are harvested, a sample of fresh semen is often taken. A previously frozen sample can also be used, though, if a fresh sample can't be made on the same day or if the spouse isn't there on the day, the eggs are collected. The sperm and the eggs will be combined by a technician in a petri dish. If it fails to result in embryos, your doctor can choose to perform ICSI.
Stage 6: Fertilizing the Eggs

The eggs will be fertilized in the laboratory, either through ICSI or traditional IVF. The embryologist will check the eggs the following day to see whether they have been fertilized and then later to see if any embryos have developed further. It is possible to freeze additional well-developed embryos if there are more than three for eventual later transfer.
Stage 7: Embryo Culture

The fertilized eggs (embryos) are nurtured in a controlled environment, allowing them to grow and develop.
Stage 8: Embryo Transfer

This is done two, three, or five days following egg harvest. To decide if a day 3 or day 5 transfer is necessary, embryologists keep an eye on the development and viability of the embryos. The embryo is positioned in your uterus using a tiny catheter that is implanted. It takes between six and ten days for the implantation to take place if the operation is successful. A course of medicines to assist the luteal phase will be provided to you after the transfer.
Stage 9: Pregnancy Test

A pregnancy blood test is carried out after two weeks following extraction. In the event that the test is positive, the patient is thought to be four weeks pregnant.

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